Detalles MARC
| 000 -LEADER |
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| fixed length control field |
03429nam a2200409 a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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| control field |
co-ctgiumayor |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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| control field |
20240708115058.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS |
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| fixed length control field |
m d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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| fixed length control field |
cr cnu---uuuuu |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
150827s2015 s 000 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9783319185392 |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
CO-CtgIUMC |
| Language of cataloging |
spa |
| Transcribing agency |
coctgiumc |
| Modifying agency |
rda |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
519.5 |
| Item number |
F981c |
| Edition number |
23 |
| 245 00 - TITLE STATEMENT |
|---|
| Title |
Fundamentals of Clinical Trials |
| Medium |
[electronic resource] / |
| Statement of responsibility, etc. |
by Lawrence M. Friedman, Curt D. Furberg, David L. DeMets, David M. Reboussin, Christopher B. Granger. |
| 250 ## - EDITION STATEMENT |
|---|
| Edition statement |
Quinta edición. |
| 264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Cham : : |
| Name of producer, publisher, distributor, manufacturer |
Springer International Publishing : : |
| -- |
Imprint: Springer,, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2015 |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Date of production, publication, distribution, manufacture, or copyright notice |
2015 |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
XXI, 550 páginas. 49 illus., 7 illus. in color. : |
| Other physical details |
online resource. |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
texto |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
|---|
| Media type term |
computador |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
recurso en línea |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc. note |
Incluye referencias bibliográficas e índice. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Introduction to Clinical Trials -- Ethical Issues -- What is the Question? -- Study Population -- Basic Study Design -- The Randomization Process -- Blinding -- Sample Size -- Baseline Assessment -- Recruitment of Study Participants -- Data Collection and Quality Control -- Assessment and Reporting of Harm -- Assessment of Health Related Quality of Life -- Participant Adherence -- Survival Analysis -- Monitoring Committee Structure & Function -- Statistical Methods Used in Interim Monitoring -- Issues in Data Analysis -- Closeout -- Reporting and Interpreting of Results -- Multicenter Trials -- Regulatory Issues. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
Este libro está dirigido al investigador clínico que esté interesado en diseñar un ensayo clínico y desarrollar un protocolo. También es valioso para los investigadores y profesionales que deben evaluar críticamente la literatura de los ensayos clínicos publicados y evaluar los méritos de cada ensayo y las implicaciones para la atención y el tratamiento de los pacientes. Los autores utilizan numerosos ejemplos de ensayos clínicos publicados para ilustrar los fundamentos. El texto se organiza secuencialmente desde la definición de la pregunta hasta el cierre del juicio. Se dedica un capítulo a cada una de las áreas críticas para ayudar al investigador del ensayo clínico. Estas áreas incluyen la especificación previa de las preguntas científicas que se probarán y las medidas de resultado apropiadas, determinar la estructura organizativa, estimar un tamaño de muestra adecuado, especificar el procedimiento de aleatorización, implementar la intervención y los horarios de visitas para la evaluación de los participantes, establecer datos provisionales y monitoreo de seguridad plan, que detalla el plan de análisis final e informa los resultados del ensayo de acuerdo con los objetivos especificados previamente. |
| 533 ## - REPRODUCTION NOTE |
|---|
| Type of reproduction |
Electronic resource. |
| Place of reproduction |
Dordrecht : |
| Agency responsible for reproduction |
Springer Netherlands, |
| Date of reproduction |
2015. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Estadística. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Oncología. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Salud pública. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Epidemiología. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Friedman, Lawrence M., |
| Dates associated with a name |
1942- |
| Relator term |
autor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Furberg, Curt, |
| Relator term |
autor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
DeMets, David L., |
| Dates associated with a name |
1944- |
| Relator term |
autor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Reboussin, David, |
| Relator term |
autor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Granger, Christopher B., |
| Relator term |
autor. |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
<a href="https://drive.google.com/file/d/1pHDoMPXJ53uUDL8J23g7WpYw3Ie9v3iw/view?usp=sharing">https://drive.google.com/file/d/1pHDoMPXJ53uUDL8J23g7WpYw3Ie9v3iw/view?usp=sharing</a> |
| Public note |
Dar click aqui para ver texto completo |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Libros electrónicos |
| Source of classification or shelving scheme |
Dewey Decimal Classification |
