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005			20240711081756.0
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007			cr cnu---uuuuu
008			171114s2017 s 000 0 eng d
020			_a9783319488486 _q(eBook)
020			_a9783319488462 _q(Hardback)
040			_aCO-CtgIUMC _bspa _ccoctgiumc _drda
082	0	4	_a616.99449 _bB828 _223
245	0	0	_aBreast cancer _h[electronic resource] : _binnovations in research and management / _cUmberto Veronesi, Aron Goldhirsch, editors-in-chief ; Paolo Veronesi, Oreste Davide Gentilini, Maria Cristina Leonardi, editors.
264		4	_aCham, Switzerland : : _bSpringer,, _c2017
264		1	_c2017
300			_a1 recurso en línea (xiv, 928 páginas) : _bilustraciones (some color)
336			_atexto _btxt _2rdacontent
337			_acomputador _bc _2rdamedia
338			_arecurso en línea _bcr _2rdacarrier
504			_aIncluye referencias bibliográficas e índice.
505	0		_aScellaneous Approaches -- Lifestyle and breast cancer -- Psychological support -- HIFU and radiofrequency as alternatives to surgery -- Hyperthermia with RT and with systemic therapies -- Electro-chemotherapy -- Circulating miRNA in early diagnosis -- Relevance  of stem cells -- Part XII Biostatistics and Bioinformatics -- Subgroup analyses and information from clinical trials on  breast cancer -- The methodology of meta analyses and its potential contribution to patient care -- Modern biostatistics  for accelerated  data acquisition for new drugs -- Bioinformatics for clinical use in breast cancer -- Efficacy endpoints in breast cancer studies and definitive  implant replacement -- Breast reconstruction with pedicled flaps -- Breast reconstruction with free flaps -- Contralateral breast management -- Fat grafting in breast reconstruction -- Breast reconstruction with biological and nonbiological  meshes -- How to manage complications in breast reconstruction -- Part VII Medical Oncology -- Adjuvant systemic therapies by subtypes: guidelines -- Primary systemic therapies: guidelines -- Treatment of advanced disease: guidelines -- Endocrine therapies in the adjuvant and advanced disease settings -- Chemotherapy regimens in the adjuvant and advanced disease settings -- Anti-HER2 therapies in the adjuvant and advanced disease settings -- Systemic therapy with bisphosphonates and anti-RANK-L agents -- Systemic treatment for specific medical situations -- Part VIII Radiotherapy -- Conceptual basis and principles of radiation oncology -- Whole breast radiation following breast-conserving surgery in invasive cancer -- Whole breast radiation following breast-conserving surgery in noninvasive cancer -- Post-mastectomy radiotherapy -- Integration of radiotherapy with systemic therapies -- Partial breast irradiation -- Intraoperative radiotherapy ELIOT -- Radiotherapy for metastatic lesions -- Part IX Special Conditions Requiring Multidisciplinary Approaches -- Emergencies in breast cancer -- Breast cancer during pregnancy -- Fertility issues in patients with newly diagnosed breast cancer -- Sexual functions and breast cancer -- Male breast cancer -- Inflammatory  breast cancer -- Treatment of CNS involvement -- Treatment of skeletal disease -- Follow-up of patients with breast cancer -- Part X Investigating New Drugs and Immunological Agents in Breast Cancer -- Targeting immune-checkpoint -- Targeting PIK3CA/AKT/mTOR -- Targeting genome instability and DNA repair -- Targeting CDK4/6 pathway -- Targeting FGFR pathway -- Integrating next generation sequencing data in trial design -- Part XI Investigational and Mi.
520			_aEste libro proporciona al lector información actualizada sobre avances importantes en la comprensión del cáncer de mama y enfoques innovadores para su manejo. Las perspectivas actuales y emergentes sobre genética, biología y prevención se analizan primero en profundidad, y las secciones individuales se dedican a patología, imagenología, cirugía oncológica, cirugía plástica y reconstructiva, oncología médica y radioterapia. En cada caso, la atención se centra en el progreso más reciente y / o las terapias y técnicas de vanguardia. Otros temas para recibir una consideración detallada incluyen condiciones particulares que requieren enfoques multidisciplinarios, la investigación de nuevos fármacos y agentes inmunológicos, aspectos de estilo de vida y psicológicos, y bioestadística e informática. El libro ser una excelente referencia para profesionales, pasantes y residentes en oncología médica, cirugía oncológica, radioterapia, patología y genética humana, investigadores y estudiantes de medicina avanzados.
650		0	_aCancer de mama _xDiagnóstico _xTratamiento.
700	1		_aVeronesi, Umberto, _eeditor.
700	1		_aGoldhirsch, A. _q(Aron), _eeditor.
700	1		_aVeronesi, Paolo, _eeditor.
700	1		_aGentilini, Oreste Davide, _eeditor.
700	1		_aLeonardi, Maria Cristina, _eeditor.
856			_uhttps://drive.google.com/file/d/1z569tnNWL2KF2tgWa_BVXT_mxcfxQq_T/view?usp=sharing _zDar click aqui para ver texto completo
942			_cCF _2ddc
999			_c87583 _d87583