Breast cancer [electronic resource] : innovations in research and management / Umberto Veronesi, Aron Goldhirsch, editors-in-chief ; Paolo Veronesi, Oreste Davide Gentilini, Maria Cristina Leonardi, editors.

Incluye referencias bibliográficas e índice.

Scellaneous Approaches -- Lifestyle and breast cancer -- Psychological support -- HIFU and radiofrequency as alternatives to surgery -- Hyperthermia with RT and with systemic therapies -- Electro-chemotherapy -- Circulating miRNA in early diagnosis -- Relevance  of stem cells -- Part XII Biostatistics and Bioinformatics -- Subgroup analyses and information from clinical trials on  breast cancer -- The methodology of meta analyses and its potential contribution to patient care -- Modern biostatistics  for accelerated  data acquisition for new drugs -- Bioinformatics for clinical use in breast cancer -- Efficacy endpoints in breast cancer studies and definitive  implant replacement -- Breast reconstruction with pedicled flaps -- Breast reconstruction with free flaps -- Contralateral breast management -- Fat grafting in breast reconstruction -- Breast reconstruction with biological and nonbiological  meshes -- How to manage complications in breast reconstruction -- Part VII Medical Oncology -- Adjuvant systemic therapies by subtypes: guidelines -- Primary systemic therapies: guidelines -- Treatment of advanced disease: guidelines -- Endocrine therapies in the adjuvant and advanced disease settings -- Chemotherapy regimens in the adjuvant and advanced disease settings -- Anti-HER2 therapies in the adjuvant and advanced disease settings -- Systemic therapy with bisphosphonates and anti-RANK-L agents -- Systemic treatment for specific medical situations -- Part VIII Radiotherapy -- Conceptual basis and principles of radiation oncology -- Whole breast radiation following breast-conserving surgery in invasive cancer -- Whole breast radiation following breast-conserving surgery in noninvasive cancer -- Post-mastectomy radiotherapy -- Integration of radiotherapy with systemic therapies -- Partial breast irradiation -- Intraoperative radiotherapy ELIOT -- Radiotherapy for metastatic lesions -- Part IX Special Conditions Requiring Multidisciplinary Approaches -- Emergencies in breast cancer -- Breast cancer during pregnancy -- Fertility issues in patients with newly diagnosed breast cancer -- Sexual functions and breast cancer -- Male breast cancer -- Inflammatory  breast cancer -- Treatment of CNS involvement -- Treatment of skeletal disease -- Follow-up of patients with breast cancer -- Part X Investigating New Drugs and Immunological Agents in Breast Cancer -- Targeting immune-checkpoint -- Targeting PIK3CA/AKT/mTOR -- Targeting genome instability and DNA repair -- Targeting CDK4/6 pathway -- Targeting FGFR pathway -- Integrating next generation sequencing data in trial design -- Part XI Investigational and Mi.

Este libro proporciona al lector información actualizada sobre avances importantes en la comprensión del cáncer de mama y enfoques innovadores para su manejo. Las perspectivas actuales y emergentes sobre genética, biología y prevención se analizan primero en profundidad, y las secciones individuales se dedican a patología, imagenología, cirugía oncológica, cirugía plástica y reconstructiva, oncología médica y radioterapia. En cada caso, la atención se centra en el progreso más reciente y / o las terapias y técnicas de vanguardia. Otros temas para recibir una consideración detallada incluyen condiciones particulares que requieren enfoques multidisciplinarios, la investigación de nuevos fármacos y agentes inmunológicos, aspectos de estilo de vida y psicológicos, y bioestadística e informática. El libro ser una excelente referencia para profesionales, pasantes y residentes en oncología médica, cirugía oncológica, radioterapia, patología y genética humana, investigadores y estudiantes de medicina avanzados.